TAK1 inhibition prevents the development of autoimmune diabetes in NOD mice

Transforming growth factor-β activated kinase-1 (TAK1, Map3k7), a member of the mitogen-activated protein kinase kinase kinase (MAP3K) family, is essential in innate and adaptive immune responses. We postulated that blockade of TAK1 would affect autoimmune diabetes in non-obese diabetic (NOD) mice....

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Detalles Bibliográficos
Autores principales: Cao, Hui, Lu, Jingli, Du, Jiao, Xia, Fei, Wei, Shouguo, Liu, Xiulan, Liu, Tingting, Liu, Yang, Xiang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602205/
https://www.ncbi.nlm.nih.gov/pubmed/26459028
http://dx.doi.org/10.1038/srep14593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602205/
https://www.ncbi.nlm.nih.gov/pubmed/26459028
http://dx.doi.org/10.1038/srep14593

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