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A simple bridging flocculation assay for rapid, sensitive and stringent detection of gene specific DNA methylation

The challenge of bringing DNA methylation biomarkers into clinic is the lack of simple methodologies as most current assays have been developed for research purposes. To address the limitations of current methods, we describe herein a novel methyl-protein domain (MBD) enrichment protocol for simple...

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Detalles Bibliográficos
Autores principales: Wee, Eugene J. H., Ha Ngo, Thu, Trau, Matt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602207/
https://www.ncbi.nlm.nih.gov/pubmed/26458746
http://dx.doi.org/10.1038/srep15028