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The eQTL-missense polymorphisms of APOBEC3H are associated with lung cancer risk in a Han Chinese population

APOBEC (Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like) enzymes may involve in mutagenic processes in multiple cancer types, including lung cancer. APOBEC family of cytidine deaminases induces base substitutions with a stringent TCW motif, which is widespread in multiple human canc...

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Detalles Bibliográficos
Autores principales: Zhu, Meng, Wang, Yuzhuo, Wang, Cheng, Shen, Wei, Liu, Jia, Geng, Liguo, Cheng, Yang, Dai, Juncheng, Jin, Guangfu, Ma, Hongxia, Hu, Zhibin, Shen, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602211/
https://www.ncbi.nlm.nih.gov/pubmed/26459911
http://dx.doi.org/10.1038/srep14969