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The first two cell-fate decisions of preimplantation mouse embryo development are not functionally independent

During mouse preimplantation embryo development, three distinct cell lineages are formed, represented by the differentiating trophectoderm (TE), primitive endoderm (PrE) and the pluripotent epiblast (EPI). Classically, lineage derivation has been presented as a two-step process whereby outer TE cell...

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Detalles Bibliográficos
Autores principales: Mihajlović, Aleksandar I., Thamodaran, Vasanth, Bruce, Alexander W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602213/
https://www.ncbi.nlm.nih.gov/pubmed/26461180
http://dx.doi.org/10.1038/srep15034