The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation

Folate metabolism is central to cell proliferation and a target of commonly used cancer chemotherapeutics. In particular, the mitochondrial folate-coupled metabolism is thought to be important for proliferating cancer cells. The enzyme MTHFD2 in this pathway is highly expressed in human tumors and b...

Descripción completa

Detalles Bibliográficos
Autores principales: Gustafsson Sheppard, Nina, Jarl, Lisa, Mahadessian, Diana, Strittmatter, Laura, Schmidt, Angelika, Madhusudan, Nikhil, Tegnér, Jesper, Lundberg, Emma K., Asplund, Anna, Jain, Mohit, Nilsson, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602236/
https://www.ncbi.nlm.nih.gov/pubmed/26461067
http://dx.doi.org/10.1038/srep15029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602236/
https://www.ncbi.nlm.nih.gov/pubmed/26461067
http://dx.doi.org/10.1038/srep15029

Ejemplares similares