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Preclinical characterisation of the GM-CSF receptor as a therapeutic target in rheumatoid arthritis

OBJECTIVE: Previous work has suggested that the granulocyte macrophage colony stimulating factor (GM-CSF)–GM-CSF receptor α axis (GM-CSFRα) may provide a new therapeutic target for the treatment of rheumatoid arthritis (RA). Therefore, we investigated the cellular expression of GM-CSFRα in RA synovi...

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Detalles Bibliográficos
Autores principales: Greven, D E A, Cohen, E S, Gerlag, D M, Campbell, J, Woods, J, Davis, N, van Nieuwenhuijze, A, Lewis, A, Heasmen, S, McCourt, M, Corkill, D, Dodd, A, Elvin, J, Statache, G, Wicks, I P, Anderson, I K, Nash, A, Sleeman, M A, Tak, P P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602263/
https://www.ncbi.nlm.nih.gov/pubmed/24936585
http://dx.doi.org/10.1136/annrheumdis-2014-205234