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NMDA receptor binding in focal epilepsies

OBJECTIVE: To demonstrate altered N-methyl-d-aspartate (NMDA) receptor availability in patients with focal epilepsies using positron emission tomography (PET) and [(18)F]GE-179, a ligand that selectively binds to the open NMDA receptor ion channel, which is thought to be overactive in epilepsy. METH...

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Detalles Bibliográficos
Autores principales: McGinnity, C J, Koepp, M J, Hammers, A, Riaño Barros, D A, Pressler, R M, Luthra, S, Jones, P A, Trigg, W, Micallef, C, Symms, M R, Brooks, D J, Duncan, J S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602274/
https://www.ncbi.nlm.nih.gov/pubmed/25991402
http://dx.doi.org/10.1136/jnnp-2014-309897