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IL12p40 Regulates Functional Development of Human CD4(+) T Cells: Enlightenment by the Elevated Expressions of IL12p40 in Patients With Inflammatory Bowel Diseases
The proinflammatory effects of IL12p40 had been documented in the literature, and anti-IL12p40 treatment had been proved to be effective in therapy of Crohn disease (CD) in a phase 2b clinical trial. However, the precise role of IL12p40 in the pathogenesis of inflammatory bowel disease (IBD) was sti...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602478/ https://www.ncbi.nlm.nih.gov/pubmed/25761185 http://dx.doi.org/10.1097/MD.0000000000000613 |