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IFNAR1 Is a Predictor for Overall Survival in Colorectal Cancer and Its mRNA Expression Correlated With IRF7 But Not TLR9

Toll-like receptor (TLR) 9 plays a role in intestinal inflammation that, in turn, is related to the tumorigenesis of colorectal cancer. Nuclear factor κB (NFκB), and interferon regulatory factor (IRF) 5 and IRF7 can be activated by TLR9 and induce the production of proinflammatory cytokines and type...

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Detalles Bibliográficos
Autores principales: Chang, Liang-Che, Fan, Chung-Wei, Tseng, Wen-Ko, Chein, Hui-Ping, Hsieh, Tsan-Yu, Chen, Jim-Ray, Hwang, Cheng-Cheng, Hua, Chung-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602595/
https://www.ncbi.nlm.nih.gov/pubmed/25546690
http://dx.doi.org/10.1097/MD.0000000000000349