XRCC2 Promotes Colorectal Cancer Cell Growth, Regulates Cell Cycle Progression, and Apoptosis

X-ray repair complementing defective repair in Chinese hamster cells 2 (XRCC2) and poly(ADP-ribose) polymerase 1 (PARP1) both play important roles in homologous recombination DNA repair. According to the theory of synthetic lethality, XRCC2-deficient cells are more sensitive to PARP1 inhibitors comp...

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Detalles Bibliográficos
Autores principales: Xu, Kaiwu, Song, Xinming, Chen, Zhihui, Qin, Changjiang, He, Yulong, Zhan, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2014
Materias:
5700
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603138/
https://www.ncbi.nlm.nih.gov/pubmed/25526472
http://dx.doi.org/10.1097/MD.0000000000000294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603138/
https://www.ncbi.nlm.nih.gov/pubmed/25526472
http://dx.doi.org/10.1097/MD.0000000000000294

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