Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1

INTRODUCTION: BTB and CNC homology 1 (Bach1) is a transcriptional repressor of Heme oxygenase-1 (HO-1), which is cytoprotective through its antioxidant effects. The objective of this study was to define the role of Bach1 in cartilage homeostasis and osteoarthritis (OA) development using in vitro mod...

Descripción completa

Detalles Bibliográficos
Autores principales: Takada, Tsuyoshi, Miyaki, Shigeru, Ishitobi, Hiroyuki, Hirai, Yuya, Nakasa, Tomoyuki, Igarashi, Kazuhiko, Lotz, Martin K., Ochi, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603301/
https://www.ncbi.nlm.nih.gov/pubmed/26458773
http://dx.doi.org/10.1186/s13075-015-0792-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603301/
https://www.ncbi.nlm.nih.gov/pubmed/26458773
http://dx.doi.org/10.1186/s13075-015-0792-1

Ejemplares similares