Pentoxifylline Neuroprotective Effects Are Possibly Related to Its Anti-Inflammatory and TNF-Alpha Inhibitory Properties, in the 6-OHDA Model of Parkinson's Disease

Pentoxifylline (PTX) is a phosphodiesterase inhibitor with anti-TNF-alpha activity, associated with its anti-inflammatory action. Considering Parkinson's disease (PD) as a neuroinflammatory disorder, the objectives were to evaluate PTX neuroprotective properties, in a model of PD. Male Wistar r...

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Detalles Bibliográficos
Autores principales: Neves, Kelly Rose Tavares, Nobre, Hélio Vitoriano, Leal, Luzia Kalyne A. M., de Andrade, Geanne Matos, Brito, Gerly Anne de Castro, Viana, Glauce Socorro de Barros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603313/
https://www.ncbi.nlm.nih.gov/pubmed/26491600
http://dx.doi.org/10.1155/2015/108179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603313/
https://www.ncbi.nlm.nih.gov/pubmed/26491600
http://dx.doi.org/10.1155/2015/108179

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