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Generation of a novel monoclonal antibody that recognizes the alpha (α)-amidated isoform of a valine residue
BACKGROUND: Alpha (α)-amidation of peptides is a mechanism required for the conversion of prohormones into functional peptide sequences that display biological activities, receptor recognition and signal transduction on target cells. Alpha (α)-amidation occurs in almost all species and amino acids i...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603347/ https://www.ncbi.nlm.nih.gov/pubmed/26463686 http://dx.doi.org/10.1186/s12868-015-0206-y |