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Generation of a novel monoclonal antibody that recognizes the alpha (α)-amidated isoform of a valine residue

BACKGROUND: Alpha (α)-amidation of peptides is a mechanism required for the conversion of prohormones into functional peptide sequences that display biological activities, receptor recognition and signal transduction on target cells. Alpha (α)-amidation occurs in almost all species and amino acids i...

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Detalles Bibliográficos
Autores principales: Antón Palma, Benito, Leff Gelman, Philippe, Medecigo Ríos, Mayra, Calva Nieves, Juan Carlos, Acevedo Ortuño, Rodolfo, Matus Ortega, Maura Epifanía, Hernández Calderón, Jorge Alberto, Hernández Miramontes, Ricardo, Flores Zamora, Anabel, Salazar Juárez, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603347/
https://www.ncbi.nlm.nih.gov/pubmed/26463686
http://dx.doi.org/10.1186/s12868-015-0206-y