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Highly Efficient Synthesis of Optically Pure (S)-1-phenyl-1,2-ethanediol by a Self-Sufficient Whole Cell Biocatalyst

Terminal vicinal diols are important chiral building blocks and intermediates in organic synthesis. Reduction of α-hydroxy ketones provides a straightforward approach to access these important compounds. In this study, it has been found that asymmetric reduction of a series of α-hydroxy aromatic ket...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Mei, Ting, Cui, Yunfeng, Chen, Qijia, Liu, Xiangtao, Feng, Jinhui, Wu, Qiaqing, Zhu, Dunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603410/
https://www.ncbi.nlm.nih.gov/pubmed/26478844
http://dx.doi.org/10.1002/open.201500045