KCNJ15/Kir4.2 couples with polyamines to sense weak extracellular electric fields in galvanotaxis

Weak electric fields guide cell migration, known as galvanotaxis/electrotaxis. The sensor(s) cells use to detect the fields remain elusive. Here we perform a large-scale screen using an RNAi library targeting ion transporters in human cells. We identify 18 genes that show either defective or increas...

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Detalles Bibliográficos
Autores principales: Nakajima, Ken-ichi, Zhu, Kan, Sun, Yao-Hui, Hegyi, Bence, Zeng, Qunli, Murphy, Christopher J., Small, J. Victor, Chen-Izu, Ye, Izumiya, Yoshihiro, Penninger, Josef M., Zhao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603535/
https://www.ncbi.nlm.nih.gov/pubmed/26449415
http://dx.doi.org/10.1038/ncomms9532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603535/
https://www.ncbi.nlm.nih.gov/pubmed/26449415
http://dx.doi.org/10.1038/ncomms9532

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