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Increased Infiltration of Extra-Cardiac Cells in Myxomatous Valve Disease

Mutations in the actin-binding gene Filamin-A have been linked to non-syndromic myxomatous valvular dystrophy and associated mitral valve prolapse. Previous studies by our group traced the adult valve defects back to developmental errors in valve interstitial cell-mediated extracellular matrix remod...

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Detalles Bibliográficos
Autores principales: Sauls, Kimberly, Toomer, Katelynn, Williams, Katherine, Johnson, Amanda J., Markwald, Roger R., Hajdu, Zoltan, Norris, Russell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603574/
https://www.ncbi.nlm.nih.gov/pubmed/26473162
http://dx.doi.org/10.3390/jcdd2030200