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Increased Infiltration of Extra-Cardiac Cells in Myxomatous Valve Disease
Mutations in the actin-binding gene Filamin-A have been linked to non-syndromic myxomatous valvular dystrophy and associated mitral valve prolapse. Previous studies by our group traced the adult valve defects back to developmental errors in valve interstitial cell-mediated extracellular matrix remod...
Autores principales: | Sauls, Kimberly, Toomer, Katelynn, Williams, Katherine, Johnson, Amanda J., Markwald, Roger R., Hajdu, Zoltan, Norris, Russell A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603574/ https://www.ncbi.nlm.nih.gov/pubmed/26473162 http://dx.doi.org/10.3390/jcdd2030200 |
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