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Reconstruction of an ancestral Yersinia pestis genome and comparison with an ancient sequence
BACKGROUND: We propose the computational reconstruction of a whole bacterial ancestral genome at the nucleotide scale, and its validation by a sequence of ancient DNA. This rare possibility is offered by an ancient sequence of the late middle ages plague agent. It has been hypothesized to be ancestr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603589/ https://www.ncbi.nlm.nih.gov/pubmed/26450112 http://dx.doi.org/10.1186/1471-2164-16-S10-S9 |