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Genetic characterization and improved genotyping of the dysferlin-deficient mouse strain Dysf(tm1Kcam)

BACKGROUND: Mouse models of dysferlinopathies are valuable tools with which to investigate the pathomechanisms underlying these diseases and to test novel therapeutic strategies. One such mouse model is the Dysf(tm1Kcam) strain, which was generated using a targeting vector to replace a 12-kb region...

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Detalles Bibliográficos
Autores principales: Wiktorowicz, Tatiana, Kinter, Jochen, Kobuke, Kazuhiro, Campbell, Kevin P., Sinnreich, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603641/
https://www.ncbi.nlm.nih.gov/pubmed/26464793
http://dx.doi.org/10.1186/s13395-015-0057-3