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Genetic characterization and improved genotyping of the dysferlin-deficient mouse strain Dysf(tm1Kcam)
BACKGROUND: Mouse models of dysferlinopathies are valuable tools with which to investigate the pathomechanisms underlying these diseases and to test novel therapeutic strategies. One such mouse model is the Dysf(tm1Kcam) strain, which was generated using a targeting vector to replace a 12-kb region...
Autores principales: | Wiktorowicz, Tatiana, Kinter, Jochen, Kobuke, Kazuhiro, Campbell, Kevin P., Sinnreich, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603641/ https://www.ncbi.nlm.nih.gov/pubmed/26464793 http://dx.doi.org/10.1186/s13395-015-0057-3 |
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