Direct Correlation Between Ligand-Induced α-Synuclein Oligomers and Amyloid-like Fibril Growth

Aggregation of proteins into amyloid deposits is the hallmark of several neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease. The suggestion that intermediate oligomeric species may be cytotoxic has led to intensified investigations of pre-fibrillar oligomers, which are complicate...

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Detalles Bibliográficos
Autores principales: Nors Perdersen, Martin, Foderà, Vito, Horvath, Istvan, van Maarschalkerweerd, Andreas, Nørgaard Toft, Katrine, Weise, Christoph, Almqvist, Fredrik, Wolf-Watz, Magnus, Wittung-Stafshede, Pernilla, Vestergaard, Bente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603703/
https://www.ncbi.nlm.nih.gov/pubmed/26020724
http://dx.doi.org/10.1038/srep10422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603703/
https://www.ncbi.nlm.nih.gov/pubmed/26020724
http://dx.doi.org/10.1038/srep10422

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