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A bioinspired peptide scaffold with high antibiotic activity and low in vivo toxicity

Bacterial resistance to almost all available antibiotics is an important public health issue. A major goal in antimicrobial drug discovery is the generation of new chemicals capable of killing pathogens with high selectivity, particularly multi-drug-resistant ones. Here we report the design, prepara...

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Detalles Bibliográficos
Autores principales: Rabanal, Francesc, Grau-Campistany, Ariadna, Vila-Farrés, Xavier, Gonzalez-Linares, Javier, Borràs, Miquel, Vila, Jordi, Manresa, Angeles, Cajal, Yolanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603705/
https://www.ncbi.nlm.nih.gov/pubmed/26024044
http://dx.doi.org/10.1038/srep10558