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A bioinspired peptide scaffold with high antibiotic activity and low in vivo toxicity
Bacterial resistance to almost all available antibiotics is an important public health issue. A major goal in antimicrobial drug discovery is the generation of new chemicals capable of killing pathogens with high selectivity, particularly multi-drug-resistant ones. Here we report the design, prepara...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603705/ https://www.ncbi.nlm.nih.gov/pubmed/26024044 http://dx.doi.org/10.1038/srep10558 |