Design, synthesis, and antitumor evaluation of histone deacetylase inhibitors with l-phenylglycine scaffold

In our previous research, a novel series of histone deacetylase (HDAC) inhibitors with l-phenylglycine scaffold were designed and synthesized, among which amides D3 and D7 and ureido D18 were far superior to the positive control (suberoylanilide hydroxamic acid [SAHA]) in HDAC inhibition, but were o...

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Detalles Bibliográficos
Autores principales: Zhang, Yingjie, Li, Xiaoguang, Hou, Jinning, Huang, Yongxue, Xu, Wenfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603714/
https://www.ncbi.nlm.nih.gov/pubmed/26504374
http://dx.doi.org/10.2147/DDDT.S94037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603714/
https://www.ncbi.nlm.nih.gov/pubmed/26504374
http://dx.doi.org/10.2147/DDDT.S94037

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