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Reconstruction of composite regulator-target splicing networks from high-throughput transcriptome data

We present a computational framework tailored for the modeling of the complex, dynamic relationships that are encountered in splicing regulation. The starting point is whole-genome transcriptomic data from high-throughput array or sequencing methods that are used to quantify gene expression and alte...

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Detalles Bibliográficos
Autores principales: Papasaikas, Panagiotis, Rao, Arvind, Huggins, Peter, Valcarcel, Juan, Lopez, A Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603746/
https://www.ncbi.nlm.nih.gov/pubmed/26449793
http://dx.doi.org/10.1186/1471-2164-16-S10-S7