Flux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism

Flux balance analysis is the only modelling approach that is capable of producing genome-wide predictions of gene essentiality that may aid to unveil metabolic liabilities in cancer. Nevertheless, a systemic validation of gene essentiality predictions by flux balance analysis is currently missing. H...

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Detalles Bibliográficos
Autores principales: Gatto, Francesco, Miess, Heike, Schulze, Almut, Nielsen, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603759/
https://www.ncbi.nlm.nih.gov/pubmed/26040780
http://dx.doi.org/10.1038/srep10738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603759/
https://www.ncbi.nlm.nih.gov/pubmed/26040780
http://dx.doi.org/10.1038/srep10738

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