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Small ubiquitin-related modifier 2/3 interacts with p65 and stabilizes it in the cytoplasm in HBV-associated hepatocellular carcinoma

BACKGROUND: SUMOylation, an important post-translational modification, associates with the development of hepatocellular carcinoma (HCC). p65, one of the most important subunits of NF-κB, is a key regulator in the development of HCC and has been reported to be SUMOylated by exogenous small ubiquitin...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Sha, Manqi, Wang, Qianfeng, Ma, Yong, Geng, Xiaoping, Gao, Yufeng, Feng, Lijie, Shen, Yujun, Shen, Yuxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603762/
https://www.ncbi.nlm.nih.gov/pubmed/26458400
http://dx.doi.org/10.1186/s12885-015-1665-3