Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine

BACKGROUND: Cancer stem cells (CSCs) are considered responsible for the recurrence and chemoresistance of cancer. Dysregulated autophagy is highly prevalent in many types of cancer including pancreatic cancer and has been implicated in cytoprotection and tumor promotion. This study aimed to investig...

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Detalles Bibliográficos
Autores principales: Yang, Ming-Chen, Wang, Hao-Chen, Hou, Ya-Chin, Tung, Hui-Ling, Chiu, Tai-Jan, Shan, Yan-Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603764/
https://www.ncbi.nlm.nih.gov/pubmed/26458814
http://dx.doi.org/10.1186/s12943-015-0449-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603764/
https://www.ncbi.nlm.nih.gov/pubmed/26458814
http://dx.doi.org/10.1186/s12943-015-0449-3

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