Comprehensive prediction of drug-protein interactions and side effects for the human proteome

Identifying unexpected drug-protein interactions is crucial for drug repurposing. We develop a comprehensive proteome scale approach that predicts human protein targets and side effects of drugs. For drug-protein interaction prediction, FINDSITE(comb), whose average precision is ~30% and recall ~27%...

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Detalles Bibliográficos
Autores principales: Zhou, Hongyi, Gao, Mu, Skolnick, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603786/
https://www.ncbi.nlm.nih.gov/pubmed/26057345
http://dx.doi.org/10.1038/srep11090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603786/
https://www.ncbi.nlm.nih.gov/pubmed/26057345
http://dx.doi.org/10.1038/srep11090

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