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HAM/TSP-derived HTLV-1-infected T cell lines promote morphological and functional changes in human astrocytes cell lines: possible role in the enhanced T cells recruitment into Central Nervous System

BACKGROUND: The mechanisms through which HTLV-1 leads to and maintains damage in the central nervous system of patients undergoing HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) are still poorly understood. In recent years, increasing evidence indicates that, not only lymphocyte...

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Detalles Bibliográficos
Autores principales: Gudo, Eduardo Samo, Silva-Barbosa, Suse Dayse, Linhares-Lacerda, Leandra, Ribeiro-Alves, Marcelo, Real, Suzana Corte, Bou-Habib, Dumith Chequer, Savino, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603815/
https://www.ncbi.nlm.nih.gov/pubmed/26458945
http://dx.doi.org/10.1186/s12985-015-0398-x