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eIF3 targets cell proliferation mRNAs for translational activation or repression

Regulation of protein synthesis is fundamental for all aspects of eukaryotic biology by controlling development, homeostasis, and stress responses(1,2). The 13-subunit, 800-kDa eukaryotic initiation factor 3 (eIF3) organizes initiation factor and ribosome interactions required for productive transla...

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Detalles Bibliográficos
Autores principales: Lee, Amy S.Y., Kranzusch, Philip J., Cate, Jamie H.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603833/
https://www.ncbi.nlm.nih.gov/pubmed/25849773
http://dx.doi.org/10.1038/nature14267