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Expression of CD1a and Type-1 Polarization Are Dissociated in Human Monocyte-Derived Dendritic Cells

Ex vivo generated monocyte-derived dendritic cell (moDC)-vaccines have long been touted as promising immunotherapeutic agents for cancer treatment, although the response rate generally remains low. The reasons for this are still unclear and confounded by the diversity in manufacturing protocols that...

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Detalles Bibliográficos
Autores principales: Mester, Brigitta, Bauer, Evelyn, Wood, Catherine E., Hermans, Ian F., Gasser, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603902/
https://www.ncbi.nlm.nih.gov/pubmed/26460687
http://dx.doi.org/10.1371/journal.pone.0140432