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Patterned polymer matrix promotes stemness and cell-cell interaction of adult stem cells
BACKGROUND: The interaction of stem cells with their culture substrates is critical in controlling their fate and function. Declining stemness of adult-derived human mesenchymal stem cells (hMSCs) during in vitro expansion on tissue culture polystyrene (TCPS) severely limits their therapeutic effica...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603908/ https://www.ncbi.nlm.nih.gov/pubmed/26464581 http://dx.doi.org/10.1186/s13036-015-0016-x |