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Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis
Immunosuppressive therapies using calcineurin inhibitors, such as cyclosporine A, are associated with a higher incidence of squamous cell carcinoma formation in mice and humans. Calcineurin is believed to suppress tumorigenesis in part through Nfatc1, a transcription factor expressed primarily in ha...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603931/ https://www.ncbi.nlm.nih.gov/pubmed/26310443 http://dx.doi.org/10.1091/mbc.E15-05-0282 |