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Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis

Immunosuppressive therapies using calcineurin inhibitors, such as cyclosporine A, are associated with a higher incidence of squamous cell carcinoma formation in mice and humans. Calcineurin is believed to suppress tumorigenesis in part through Nfatc1, a transcription factor expressed primarily in ha...

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Detalles Bibliográficos
Autores principales: Goldstein, Jill, Roth, Eve, Roberts, Natalie, Zwick, Rachel, Lin, Samantha, Fletcher, Sean, Tadeu, Ana, Wu, Christine, Beck, Amanda, Zeiss, Caroline, Suárez-Fariñas, Mayte, Horsley, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603931/
https://www.ncbi.nlm.nih.gov/pubmed/26310443
http://dx.doi.org/10.1091/mbc.E15-05-0282