The function and dynamics of the apical scaffolding protein E3KARP are regulated by cell-cycle phosphorylation

We examine the dynamics and function of the apical scaffolding protein E3KARP/NHERF2, which consists of two PDZ domains and a tail containing an ezrin-binding domain. The exchange rate of E3KARP is greatly enhanced during mitosis due to phosphorylation at Ser-303 in its tail region. Whereas E3KARP c...

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Detalles Bibliográficos
Autores principales: Sauvanet, Cécile, Garbett, Damien, Bretscher, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603932/
https://www.ncbi.nlm.nih.gov/pubmed/26310448
http://dx.doi.org/10.1091/mbc.E15-07-0498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603932/
https://www.ncbi.nlm.nih.gov/pubmed/26310448
http://dx.doi.org/10.1091/mbc.E15-07-0498

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