Cargando…

The interaction of Gα(13) with integrin β(1) mediates cell migration by dynamic regulation of RhoA

Heterotrimeric G protein Gα(13) is known to transmit G protein–coupled receptor (GPCR) signals leading to activation of RhoA and plays a role in cell migration. The mechanism underlying the role of Gα(13) in cell migration, however, remains unclear. Recently we found that Gα(13) interacts with the c...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Bo, Estevez, Brian, Xu, Zheng, Kreutz, Barry, Karginov, Andrei, Bai, Yanyan, Qian, Feng, Norifumi, Urao, Mosher, Deane, Du, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603935/
https://www.ncbi.nlm.nih.gov/pubmed/26310447
http://dx.doi.org/10.1091/mbc.E15-05-0274