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Transglutaminase binding fusion protein linked to SLPI reduced corneal inflammation and neovascularization

BACKGROUND: To study the effect of topical administration of a fusion protein (PF-MC) made up of N-terminal portion of the protease inhibitor Trappin-2 (which is a substrate of transglutaminasa-2) and SLPI (protein with anti-inflammatory, anti-bacterial and anti-viral ability), in an animal model of...

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Detalles Bibliográficos
Autores principales: Salica, Juan P, Guerrieri, Diego, Maffia, Paulo, Croxatto, Juan O, Chuluyan, H Eduardo, Gallo, Juan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603969/
https://www.ncbi.nlm.nih.gov/pubmed/25651862
http://dx.doi.org/10.1186/1471-2415-15-12