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MiRNA-621 sensitizes breast cancer to chemotherapy by suppressing FBXO11 and enhancing p53 activity

MicroRNAs (miRNAs) have been demonstrated to have critical roles in regulating cancer cell proliferation, survival and sensitivity to chemotherapy. The potential application of using miRNAs to predict therapeutic response to cancer treatment holds high promise, but miRNAs with predictive value remai...

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Detalles Bibliográficos
Autores principales: Xue, J, Chi, Y, Chen, Y, Huang, S, Ye, X, Niu, J, Wang, W, Pfeffer, L M, Shao, Z-m, Wu, Z-H, Wu, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603999/
https://www.ncbi.nlm.nih.gov/pubmed/25867061
http://dx.doi.org/10.1038/onc.2015.96