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Pigment Epithelium-Derived Factor (PEDF) Inhibits Wnt/β-catenin Signaling in the Liver

BACKGROUND & AIMS: Pigment epithelium-derived factor (PEDF) is a secretory protein that inhibits multiple tumor types. PEDF inhibits the Wnt coreceptor, low-density lipoprotein receptor-related protein 6 (LRP6), in the eye, but whether the tumor-suppressive properties of PEDF occur in organs suc...

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Detalles Bibliográficos
Autores principales: Protiva, Petr, Gong, Jingjing, Sreekumar, Bharath, Torres, Richard, Zhang, Xuchen, Belinsky, Glenn S., Cornwell, Mona, Crawford, Susan E., Iwakiri, Yasuko, Chung, Chuhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604042/
https://www.ncbi.nlm.nih.gov/pubmed/26473164
http://dx.doi.org/10.1016/j.jcmgh.2015.06.006