A Lysine Cluster in Domain II of Bacillus subtilis PBP4a Plays a Role in the Membrane Attachment of This C1-PBP

In PBP4a, a Bacillus subtilis class-C1 penicillin-binding protein (PBP), four clustered lysine (K) residues, K86, K114, K119, and K265, protrude from domain II. Replacement of these amino acids with glutamine (Q) residues by site-directed mutagenesis yielded Mut4KQ PBP4a. When produced in Escherichi...

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Detalles Bibliográficos
Autores principales: Vanden Broeck, Arnaud, Van der Heiden, Edwige, Sauvage, Eric, Dauvin, Marjorie, Joris, Bernard, Duez, Colette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604126/
https://www.ncbi.nlm.nih.gov/pubmed/26460848
http://dx.doi.org/10.1371/journal.pone.0140082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604126/
https://www.ncbi.nlm.nih.gov/pubmed/26460848
http://dx.doi.org/10.1371/journal.pone.0140082

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