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Histopathological evaluation of the ocular-irritation potential of shampoos, make-up removers and cleansing foams in the bovine corneal opacity and permeability assay

The bovine corneal opacity and permeability (BCOP) assay is an alternative method to the in vivo Draize eye test in rabbits for evaluating eye irritation in vitro. Here, we compared the numerical results of the BCOP assay with the corresponding histopathology for three different corneas for each tes...

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Detalles Bibliográficos
Autores principales: Furukawa, Masatoshi, Sakakibara, Takashi, Itoh, Kouta, Kawamura, Kohtaro, Sasaki, Satoshi, Matsuura, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604136/
https://www.ncbi.nlm.nih.gov/pubmed/26538816
http://dx.doi.org/10.1293/tox.2015-0022