Improved Safety, Bioavailability and Pharmacokinetics of Zidovudine through Lactoferrin Nanoparticles during Oral Administration in Rats

Zidovudine (AZT) is one of the most referred antiretroviral drug. In spite of its higher bioavailability (50–75%) the most important reason of its cessation are bone marrow suppression, anemia, neutropenia and various organs related toxicities. This study aims at the improvement of oral delivery of...

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Detalles Bibliográficos
Autores principales: Kumar, Prashant, Lakshmi, Yeruva Samrajya, C., Bhaskar, Golla, Kishore, Kondapi, Anand K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604150/
https://www.ncbi.nlm.nih.gov/pubmed/26461917
http://dx.doi.org/10.1371/journal.pone.0140399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604150/
https://www.ncbi.nlm.nih.gov/pubmed/26461917
http://dx.doi.org/10.1371/journal.pone.0140399

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