Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice

AIM: Cardiac inflammation is important in the pathogenesis of heart failure. However, the consequence of systemic inflammation on concomitant established heart failure, and in particular diastolic heart failure, is less explored. Here we investigated the impact of systemic inflammation, caused by su...

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Detalles Bibliográficos
Autores principales: Dhondup, Yangchen, Sjaastad, Ivar, Scott, Helge, Sandanger, Øystein, Zhang, Lili, Haugstad, Solveig Bjærum, Aronsen, Jan Magnus, Ranheim, Trine, Holmen, Sigve Dhondup, Alfsnes, Katrine, Ahmed, Muhammad Shakil, Attramadal, Håvard, Gullestad, Lars, Aukrust, Pål, Christensen, Geir, Yndestad, Arne, Vinge, Leif Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604200/
https://www.ncbi.nlm.nih.gov/pubmed/26461521
http://dx.doi.org/10.1371/journal.pone.0139715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604200/
https://www.ncbi.nlm.nih.gov/pubmed/26461521
http://dx.doi.org/10.1371/journal.pone.0139715

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