Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice

Amyloidopathy involves the accumulation of insoluble amyloid β (Aβ) species in the brain’s parenchyma and is a key histopathological hallmark of Alzheimer’s disease (AD). Work on transgenic mice that overexpress Aβ suggests that elevated Aβ levels in the brain are associated with aberrant epileptifo...

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Detalles Bibliográficos
Autores principales: Tamagnini, Francesco, Novelia, Janet, Kerrigan, Talitha L., Brown, Jon T., Tsaneva-Atanasova, Krasimira, Randall, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604241/
https://www.ncbi.nlm.nih.gov/pubmed/26528126
http://dx.doi.org/10.3389/fncel.2015.00372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604241/
https://www.ncbi.nlm.nih.gov/pubmed/26528126
http://dx.doi.org/10.3389/fncel.2015.00372

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