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Full length talin stimulates integrin activation and axon regeneration

Integrin function is regulated by activation involving conformational changes that modulate ligand-binding affinity and downstream signaling. Activation is regulated through inside-out signaling which is controlled by many signaling pathways via a final common pathway through kindlin and talin, whic...

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Detalles Bibliográficos
Autores principales: Tan, Chin Lik, Kwok, Jessica C.F., Heller, Janosch P.D., Zhao, Rongrong, Eva, Richard, Fawcett, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604251/
https://www.ncbi.nlm.nih.gov/pubmed/25771432
http://dx.doi.org/10.1016/j.mcn.2015.03.011