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Full length talin stimulates integrin activation and axon regeneration
Integrin function is regulated by activation involving conformational changes that modulate ligand-binding affinity and downstream signaling. Activation is regulated through inside-out signaling which is controlled by many signaling pathways via a final common pathway through kindlin and talin, whic...
Autores principales: | Tan, Chin Lik, Kwok, Jessica C.F., Heller, Janosch P.D., Zhao, Rongrong, Eva, Richard, Fawcett, James W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604251/ https://www.ncbi.nlm.nih.gov/pubmed/25771432 http://dx.doi.org/10.1016/j.mcn.2015.03.011 |
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