Bortezomib modulates CHIT1 and YKL40 in monocyte-derived osteoclast and in myeloma cells

Osteolytic bone disease is a common manifestation of multiple myeloma (MM) that leads to progressive skeleton destruction and is the most severe cause of morbidity in MM patients. It results from increased osteolytic activity and decrease osteoblastic function. Activation of mammalian chitinases chi...

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Detalles Bibliográficos
Autores principales: Tibullo, Daniele, Di Rosa, Michelino, Giallongo, Cesarina, La Cava, Piera, Parrinello, Nunziatina L., Romano, Alessandra, Conticello, Concetta, Brundo, Maria V., Saccone, Salvatore, Malaguarnera, Lucia, Di Raimondo, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604315/
https://www.ncbi.nlm.nih.gov/pubmed/26528182
http://dx.doi.org/10.3389/fphar.2015.00226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604315/
https://www.ncbi.nlm.nih.gov/pubmed/26528182
http://dx.doi.org/10.3389/fphar.2015.00226

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