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Dynamic enhancer–gene body contacts during transcription elongation

Enhancers govern transcription through multiple mechanisms, including the regulation of elongation by RNA polymerase II (RNAPII). We characterized the dynamics of looped enhancer contacts during synchronous transcription elongation. We found that many distal enhancers form stable contacts with their...

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Detalles Bibliográficos
Autores principales: Lee, Kiwon, Hsiung, Chris C.-S., Huang, Peng, Raj, Arjun, Blobel, Gerd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604340/
https://www.ncbi.nlm.nih.gov/pubmed/26443845
http://dx.doi.org/10.1101/gad.255265.114