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Role of the small subunit processome in the maintenance of pluripotent stem cells

RNA-binding proteins (RBPs) play integral roles in gene regulation, yet only a small fraction of RBPs has been studied in the context of stem cells. Here we applied an RNAi screen for RBPs in mouse embryonic stem cells (ESCs) and identified 16 RBPs involved in pluripotency maintenance. Interestingly...

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Detalles Bibliográficos
Autores principales: You, Kwon Tae, Park, Joha, Kim, V. Narry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604342/
https://www.ncbi.nlm.nih.gov/pubmed/26443847
http://dx.doi.org/10.1101/gad.267112.115